Pathological Response to Kidney Injury


Left kidney from an 11-year-old domestic cat with acute kidney failure (blood creatinine = 18.3mg/dl; normal = 0.5 to 2.1) due to urinary obstruction from a calcium oxalate stone lodged in the ureter.  After a poor response to conservative therapy, the cat was humanely euthanized and the kidneys were removed and scanned.  The micro CT of the left kidney revealed segmental radiating pathologic mineralization of the parenchyma (Left image) resulting from a previous infarction.  In addition, several small stones (Right image) were detected in a different location.  These mineralizations were not detected by ante mortem survey radiography.